Toward that end, researchers at University of Zurich, the Technical University Eindhoven, and the Charité Berlin, have developed computer simulations that help to predict how cultured valves will establish themselves, grow, and eventually function once inside the body.
“Thanks to the simulations, we can optimize the design and composition of the regenerative heart valves and develop customized implants for use in therapy,” in a published statement said Simon P. Hoerstrupof of the Institute of Regenerative Medicine at the University of Zurich.
So far the approach has been tried on sheep and it has proven to be quite accurate. It is hoped that this approach can be transferred quickly to the clinical realm.
Study in Science Translational Medicine: Computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model…
Via: University of Zurich…
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